Cholestenol Delta-isomerase

cholestenol delta-isomerase
Identifiers
EC number 5.3.3.5
CAS number 37318-47-1
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a cholestenol Delta-isomerase (EC 5.3.3.5) is an enzyme that catalyzes the chemical reaction

5alpha-cholest-7-en-3beta-ol \rightleftharpoons 5alpha-cholest-8-en-3beta-ol

Hence, this enzyme has one substrate, 5alpha-cholest-7-en-3beta-ol, and one product, 5alpha-cholest-8-en-3beta-ol.

This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases transposing C=C bonds. The systematic name of this enzyme class is Delta7-cholestenol Delta7-Delta8-isomerase. This enzyme participates in biosynthesis of steroids.

References

Isomerases: intramolecular oxidoreductases (EC 5.3)
5.3.1: Aldoses/Ketoses
5.3.2: Keto/Enol
5.3.3: C=C
5.3.4: S-S
5.3.99: other
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6